糖尿病肾病(DN)是糖尿病患者最严重的并发症之一,也是糖尿病最重要的致死、致残原因之一。1999年国内初步统计,它是国内导致终末肾衰竭的第二位疾病,占全部透析患者的13.3%[1]。老年糖尿病患者由于多伴有高血压、动脉硬化,且多起病隐匿、病程长,故其肾脏病变不仅发病率高,而且 Diabetic nephropathy (DN) is one of the most serious complication of diabetes and one of the most important cause of death and disability of diabetes mellitus. According to preliminary statistics in 1999, it is the second disease in China that causes terminal renal failure, accounting for 13.3% of all dialysis patients [1]. As elderly patients with diabetes often accompanied by high blood pressure, arteriosclerosis, and more insidious onset, longer duration, so the incidence of renal disease is not only high, but also