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利血平用作降血压药物已是众所周知的事,但通常所用剂型仅限于片剂和注射剂,一向依靠进口。去年大跃进以后,片剂本国已能大量生产供应市场需要,但注射剂供应仍缺。片剂口服疗效不佳或有时未见疗效,且小孩口服因味苦而致吐。为此,我们乃试图改变给药途径,做成栓剂应用。根据初步临床观察,认为有效。在应用片剂疗效慢、不佳或不见效情况下,能收到预期的治疗效果。迄今曾试用过七例(无病历可查者未计算在内),效果都很好,现将其制造方法及临床病例分述如下:
It is well known that reserpine is used as a hypotensive drug, but the dosage forms usually used are limited to tablets and injections and have always been imported. After the Great Leap Forward last year, the tablet country had been able to mass-produce its supply market needs, but the supply of injectables was still lacking. Oral oral poor efficacy or sometimes no effect, and children oral taste due to bitter and spit. To this end, we are trying to change the route of administration, making suppository application. According to preliminary clinical observation, that effective. In the application of tablets slow, poor or ineffective circumstances, can receive the expected treatment effect. So far have tried seven cases (no medical records were not included), the effect is very good, now its manufacturing methods and clinical cases are described below: