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根据Fry等作者1980年提出的多系统脏器衰竭(Multiple System Organ Failare,MSOF)诊断标准:“1、呼吸衰竭:严重的低氧血症需要机械支持通气48h以上;2、肾功能衰竭:适当补充血容量后肌酐清除率仍<50ml/min或Bu N>40mg/
According to the diagnostic criteria for multiple system organ failure (MSOF) proposed by Fry et al. In 1980: 1. Respiratory failure: Severe hypoxemia requires mechanical ventilation for more than 48 hours; 2. Renal failure: appropriate Creatinine clearance remained <50 ml / min or Bu N> 40 mg /