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Ⅱ号氟碳代血液经动物实验显示它的安全性之后,于1982年8月至1986年5月在神经外科术中输注及治疗缺血性脑血管病共40例,取得了良好的效果。本研究37例用于术中作为代血液及血液稀释输注,术中输注包括急性颅脑损伤、颅内肿瘤和脊髓肿瘤等,3例用于脑缺血性闭塞性脑血管病。急性缺血性脑血管病例,并用Ⅱ号氟碳代血液和20甘露醇溶液,氟碳代血液总剂量不超过1500ml。本研究在输注氟碳代血液前后,对一般情况、生命体征、神经体征、心电图、血气分析、血小板计数、免疫和肝肾功能等作为临床研究的客观指标。本组37例术中未输库血7例,占18.9%。输注Ⅱ号氟碳代血液后,全部病例血压等生命体征平稳,术中出现失血性休克病例,输注后血压明显上升,3例缺血性脑血管病输注后,肌力等神经体
Fluorocarbon Ⅱ blood after animal experiments showed its safety, in August 1982 to May 1986 in the Department of Neurosurgery infusion and treatment of ischemic cerebrovascular disease in 40 cases, and achieved good results . In this study, 37 cases were used as intraoperative blood transfusion and hemodilution infusion, intraoperative infusion including acute craniocerebral injury, intracranial tumors and spinal cord tumors, and 3 cases for cerebral ischemic occlusive cerebrovascular disease. Acute ischemic cerebrovascular cases, and with No. 2 fluorocarbon blood and 20 mannitol solution, fluorocarbon total dose of blood does not exceed 1500ml. This study before and after the infusion of fluorocarbon blood on the general situation, vital signs, neurological signs, ECG, blood gas analysis, platelet count, immune and liver and kidney function as an objective indicator of clinical research. The group of 37 cases of intraoperative blood transfusion in 7 cases, accounting for 18.9%. Infusion of fluorocarbon Ⅱ blood, all cases of blood pressure and other vital signs stable, intraoperative hemorrhagic shock cases, blood pressure increased significantly after infusion, 3 cases of ischemic cerebrovascular disease infusion, muscle strength and other nerve