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目的 :探讨壮族人 2型糖尿病 (T2DM )及糖尿病慢性血管并发症 (CVCD)与ABO血型的相关性。方法 :采用玻片凝集法进行ABO血型鉴定 ,调查我院壮族T2DM患者 2 47例 (合并CVCD 44例 )的ABO血型分布 ,并行疾病与血型的关联分析。以壮族健康人ABO血型分布资料作对照。结果 :T2DM患者中O型血者所占比例高于正常对照组 ,A型血者所占比例低于正常对照组。经采用Woolf推荐的血型和疾病关联性的分析方法 ,可认为O型血者患T2DM和CVCD的机率分别为非O型血者的 1.80 91和 2 .5 92 1倍 ( P <0 .0 1)。结论 :血型与T2DM、CVCD发病可能有一定关联 ,O型血的壮族人可能是T2DM、CVCD的高危人群
Objective: To investigate the relationship between type 2 diabetes mellitus (T2DM) and diabetic chronic vascular complications (CVCD) in Zhuang and ABO blood group. Methods: The ABO blood group was identified by slide agglutination method. The distribution of ABO blood group was analyzed in 477 T2DM patients (44 cases with CVCD) in our hospital. The correlation between disease and blood type was analyzed. The Zhuo healthy ABO blood group distribution data as a control. Results: The proportion of type O blood in T2DM patients was higher than that in normal controls, and the proportion of type A blood was lower than that in normal controls. By using Woolf’s recommended method of analyzing the association of blood type with disease, the odds of T2DM and CVCD in type O blood are considered to be 1.80 91 and 2.92 times (P <0.01) for non-O blood type ). Conclusion: The blood type may be related to the incidence of T2DM and CVCD. Zhuang O type blood may be the high risk group of T2DM and CVCD