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目的:探讨正常妊娠妇女卵泡休止素(FS)水平变化及其临床意义。方法:采用FS双抗体酶联免疫吸附试验(ELISA)测定210例妊娠晚期妇女的血清FS水平,同时测定51例妊娠晚期妇女血清中游离雌三醇(FE3)的水平,并分析其与FS的关系。结果:血清中FS浓度随着孕周的增加而升高,与孕周呈正相关。建立正常妊娠晚期每相邻两周血清FS参考值。妊娠晚期FS水平变化与FE3变化呈正相关。结论:FS可作为估计孕周、判定胎儿-胎盘单位功能的一项生化指标。
Objective: To investigate the changes of follicular restactin (FS) in normal pregnant women and its clinical significance. Methods: Serum FS levels were measured in 210 women with late pregnancy by FS double antibody enzyme linked immunosorbent assay (ELISA). The level of serum free estriol (FE3) in 51 women with third trimester pregnancy was measured. relationship. Results: Serum FS concentration increased with gestational age and positively correlated with gestational age. Establishment of normal pregnancy every two weeks adjacent to the serum FS reference value. Changes in the level of late pregnancy FS and FE3 changes was positively correlated. Conclusion: FS can be used as a biochemical index for estimating gestational age and determining the function of fetal-placenta.