ｔ(14;18)及ｔ(3:14) (ｑ2 7:ｑ32 )是Ｂ系淋巴瘤中最常见的两种染色体易位 ,分别为第 1位和第 3位 ,这两种易位导致了ｂｃｌ 2、ｂｃｌ 6原癌基因的激活 ,它们与Ｂ淋巴细胞的凋亡和分化有关 ,在其发育的不同阶段起作用。我们应用ＳＰ免疫组化方法检测了两种蛋白在非霍奇金淋巴 t(14;18) and t(3:14) (q2 7:q32) are the two most common chromosomal translocations in B-type lymphomas, which are the first and third positions, respectively. Activation of bcl 2 and bcl 6 proto-oncogenes, which are involved in the apoptosis and differentiation of B lymphocytes, play a role in different stages of their development. We used SP immunohistochemistry to detect two proteins in non-Hodgkin’s lymph