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目的:随着孕周增加观察孕妇体内血清抗体滴度动态变化。方法:对122例O型孕妇用凝胶法检测血清抗体效价。结果:血清抗体首次检测37例(30.3%)IgG抗A(B)效价≥128,其中23例(18.8%)IgG抗A(B)效价≥256;末次检测29例(23.8%)IgG抗A(B)效价≥128,其中16例(13..1%)IgG抗A(B)效价≥256。14例抗体滴度不同程度升高,38例抗体滴度不同程度降低。结论:血清学检查针对预防新生儿溶血病是一项十分必要的检测手段,而孕妇体内血清抗体的动态观察更有利于临床早期诊断,早期预防和早期治疗。
OBJECTIVE: To observe the dynamic changes of serum antibody titer in pregnant women with gestational age. Methods: 122 cases of O pregnant women with gel method to detect serum antibody titer. RESULTS: Totally 37 (30.3%) IgG anti-A (B) titers ≥128 were detected in the serum samples. Twenty-three (18.8%) IgG anti-A Anti-A (B) titer ≥128, of which 16 (13..1%) IgG anti-A (B) titer ≥256.14 cases of antibody titer increased to varying degrees, 38 cases of antibody titer decreased to varying degrees. Conclusion: Serological tests are very necessary to prevent neonatal hemolytic disease. Dynamic observation of serum antibodies in pregnant women is more conducive to early clinical diagnosis, early prevention and early treatment.