博尔纳病病毒(BDV)是在人与哺乳动物间自然传播的一种动物病原体,人体感染BDV后可导致病毒相关基因组发生变化。目前,随着BDV检测方法的不断发展,检测出的BDV感染例数不断增加,给患者及社会带来沉重的经济负担。本文对BDV的流行病学、病原学、治疗及预防进行综述,为临床提供参考。 Borna disease virus (BDV) is an animal pathogen naturally transmitted between humans and mammals. Infection with BDV leads to changes in the virus-associated genome. At present, with the continuous development of BDV detection methods, the number of detected BDV infections is continuously increasing, which brings a heavy financial burden to patients and society. This article summarizes the epidemiology, etiology, treatment and prevention of BDV, providing reference for clinical practice.