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轻链病是由于病态浆细胞产生的轻链过多,而重链合成则相应减少,以致过多的游离轻链及其片段出现于血浆和尿液中。这种只有凝溶蛋白单独出现而不伴有其它任何单细胞系Ig的增多,称为轻链病。近年来随着免疫化学诊断技术的提高。国内已能制备Kappa型和Lambde型轻链抗血清,这就为诊断轻链病从细胞学水平提高到分子学水平提供了条件,并使本病检出率有所增加。本病目前国内已有零星报导。最近我院发现一例Lambda型轻链病现报告如下: 患者刘××女63岁住院号
Light chain disease is caused by too much light chain from diseased plasma cells and a corresponding decrease in heavy chain synthesis, resulting in excessive free light chains and fragments thereof in plasma and urine. This only appears to be protein coagulation protein alone without any other single-cell Ig increased, known as light chain disease. In recent years, with the improvement of immunochemical diagnostic techniques. China has been able to prepare Kappa and Lambde type light chain antiserum, which for the diagnosis of light chain disease from cytology to improve the level of molecular biology provides the conditions and the detection rate of the disease increased. The disease is currently sporadic reports. Recently, our hospital found a case of Lambda-type light chain disease are reported as follows: Patients Liu × × female 63-year-old hospital number