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1950年抗生素的广泛商品化,引起导致人类死亡的疾病从感染性/急性到非感染性/慢性的转化。在这种情况下,人们希望并非以选择性毒性为基础的生物反应调节剂(BRMS)能够起作用。BRMS,包括直接作用于细胞基因表达水平的视黄醛和调节身体内环境的反应停(及其相关分子)。
The widespread commercialization of antibiotics in 1950 led to the conversion from infectious / acute to non-infectious / chronic diseases leading to human death. Under these circumstances, it is hoped that a biological response modifier (BRMS) that is not based on selective toxicity will work. BRMS, including retinal, which acts directly on cellular gene expression levels and response stops (and their associated molecules) that regulate the environment in the body.