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本文报道约氏疟原虫—斯氏按蚊系统的实验动物模型及用其筛选杀组织期抗疟药的结果,同时介绍了对测定红细胞前期药物作用的筛选方法。结果表明,模型和方法对筛选根治和病因性预防等杀组织期抗疟药物有实用价值。
This article reports the experimental animal model of Plasmodium yoelii-An. Mosquitoes and the results of screening the anti-malarial drugs in the period of killing the tissue. Meanwhile, the screening method for determining the effect of the erythrocyte pre-drug was introduced. The results show that the model and method have practical value in screening anti-malarial drugs such as radical and etiological prevention and other anti-malarial drugs.