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目的对血清胱抑素C在糖尿病肾功能检测中的临床意义进行分析探讨。方法随机抽取在2010年6月至2012年6月间我院收治的2型糖尿病肾病患者病例36例、单纯糖尿病患者病例35例以及同期健康体检者40例作为研究对象,对这3组研究对象先后展开血清胱抑素C、血肌酐、尿素氮、β2-微球蛋白水平检测,并对比分析3组的检测结果。结果糖尿病肾病组和单纯糖尿病组患者的以上四项检测指标均显著高于健康组(P<0.05);且糖尿病肾病组患者的血清胱抑素C、血肌酐检测水平较单纯糖尿病组高(P<0.05)。结论对针对糖尿病肾病患者而言,血清胱抑素C的检测对肾功能评价具有重要意义,值得给予关注。
Objective To analyze the clinical significance of serum cystatin C in the detection of diabetic renal function. Methods Totally 36 patients with type 2 diabetic nephropathy, 35 patients with simple diabetes mellitus and 40 healthy subjects at the same period were selected randomly from June 2010 to June 2012 in our hospital. Has carried out serum cystatin C, serum creatinine, urea nitrogen, β2-microglobulin levels, and comparative analysis of the three groups of test results. Results The above four indexes in diabetic nephropathy group and simple diabetic group were significantly higher than those in healthy group (P <0.05). The levels of serum cystatin C and serum creatinine in diabetic nephropathy group were higher than those in simple diabetic group <0.05). Conclusion For patients with diabetic nephropathy, serum cystatin C detection of renal function evaluation of great significance, it deserves attention.