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目的:为了了解腹腔肿瘤病人手术前后免疫功能情况.方法:本文采用ELISA法检测了30例正常健康人群和35例腹腔肿瘤病人手术前后血清可溶性白细胞介素-2受体(SIL-2R)和肿瘤坏死因子(TNF)水平.结果:显示腹腔肿瘤病人血清SIL-2R和TNF值水平明显高于正常对照组(P<0.05),手术后7天SIL-2R和TNF开始逐渐下降15天后SIL-2R和TNF明显下降,未手术病人SIL-2R和TNF持续增高.结论:在临床上动态检测血清SIL-2R和TNF其水平变化可作为腹腔肿瘤患者的病情在判断、疗效观察及估计预后的参考指标.
Objective: To understand the preoperative and postoperative immune function of patients with abdominal cavity tumors. Methods: Serum soluble interleukin-2 receptor (SIL-2R) and tumors in 30 normal healthy subjects and 35 patients with abdominal tumors were examined by ELISA before and after surgery. TNF levels. Results: The serum levels of SIL-2R and TNF in patients with peritoneal cancer were significantly higher than those in the normal control group (P<0.05). SIL-2R and TNF began to decline after 7 days of surgery. 15 days after SIL-2R Both TNF and TNF decreased significantly, and SIL-2R and TNF in unoperated patients continued to increase. Conclusion: Dynamic detection of serum levels of SIL-2R and TNF in patients with peritoneal tumors can be used as a reference for judging the disease condition, observing the curative effect, and estimating the prognosis. .