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近年来,配方工程师在回顾了预胶化淀粉作为黏合剂、崩解剂和填充剂的传统用途之后,又发现了其新用途,如预胶化淀粉可以优先结合水分而增强药物的稳定性,以及在开发缓释制剂时用来控制药物的释放速率。美国药典中对预胶化淀粉的定义是“采用化学的或机械的方法使淀粉在有水存在时全部或部分颗粒破碎,然后干燥。经过改性,提高了它的可压性和流动性”。但它并没有详细说明淀粉的胶化或改性的程度,
In recent years, after reviewing the traditional use of pregelatinized starch as binders, disintegrants and fillers, formulators have found new uses such as pregelatinized starch that preferentially binds to water to enhance the stability of the drug, As well as to control the rate of drug release when developing sustained release formulations. The definition of pregelatinized starch in the United States Pharmacopeia is that “chemical or mechanical methods are used to break all or part of the starch in the presence of water and then dry it. It is modified to improve its compressibility and fluidity ”. However, it does not specify the degree of gelatinization or modification of the starch,