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目的:探讨省名中医验方补虚化毒方联合化疗治疗晚期非小细胞肺癌的临床效果。方法:选择经过病理组织学和/或细胞学检查确诊的晚期非小细胞肺癌患者,随机分为治疗组和对照组,每组30例。对照组采用GP或TP方案化疗;治疗组在相同化疗的基础上服用补虚化毒方(灵芝、薏苡仁、虎眼万年青等)。比较两组的临床疗效。结果:治疗组和对照组的总有效率(CR+PR)分别为40.0%、13.3%,疾病控制率(CR+PR+SD)分别为86.7%、66.7%。在临床证候、体力状况、CEA值变化、不良反应等方面,治疗组均优于对照组。
Objective: To investigate the clinical effect of the provincial traditional Chinese medicine prescription Buxuhua Tidu combined chemotherapy in the treatment of advanced non-small cell lung cancer. Methods: Patients with advanced non-small cell lung cancer diagnosed by histopathology and / or cytology were randomly divided into treatment group and control group, with 30 cases in each group. The control group was treated with GP or TP regimen; the treatment group took Buxuhuadu (Ganoderma lucidum, Coix seed, Ornithogalum, etc.) on the same basis of chemotherapy. The clinical efficacy of the two groups was compared. Results: The total effective rate (CR + PR) of the treatment group and the control group were 40.0% and 13.3% respectively, and the disease control rates (CR + PR + SD) were 86.7% and 66.7% respectively. In the clinical syndromes, physical status, CEA changes, adverse reactions, the treatment group were better than the control group.