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目的探讨重症脑炎患儿早期肠内和肠外营养支持治疗的对比分析。方法将2011年8月至2012年8月周口市中心医院诊治的48例重症脑炎患儿随机分为肠内营养组和肠外营养组,分别给予相应的营养支持治疗,对两组治疗前后血清白蛋白(ALB)、丙氨酸氨基转移酶(ALT)、血糖(GLU)的变化情况,重症监护室住院时间、住院费用以及并发症发生率等进行观察和比较。结果与肠外营养组相比,肠内营养治疗后ALB明显增高,ALT、GLU水平明显降低,并发症发生率、重症监护室住院时间、住院费用均明显降低,差异有统计学意义(P<0.05)。结论对于重症脑炎患儿,早期应给予肠内营养支持能够改善患儿的预后质量,促进脑损伤后胃肠动力的恢复。
Objective To investigate the comparative analysis of early enteral and parenteral nutritional support in children with severe encephalitis. Methods Forty-eight cases of severe encephalitis diagnosed and treated in the Central Hospital of Zhoukou from August 2011 to August 2012 were randomly divided into enteral nutrition group and parenteral nutrition group, and were given corresponding nutrition supportive treatment. Before and after treatment Serum albumin (ALB), alanine aminotransferase (ALT), blood glucose (GLU) changes, intensive care unit hospitalization, hospitalization costs and the incidence of complications were observed and compared. Results Compared with parenteral nutrition group, ALB was significantly increased after enteral nutrition treatment, the levels of ALT and GLU were significantly decreased, the incidence of complications, hospital stay in intensive care unit and hospitalization costs were significantly decreased (P < 0.05). Conclusion For children with severe encephalitis, early enteral nutrition should be given to improve the prognosis of children and to promote the recovery of gastrointestinal motility after brain injury.