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目的探讨盐酸戊乙奎醚治疗急性有机磷农药中毒的临床效果。方法将我院106例有机磷农药中毒患者分为两组,观察组56例采用盐酸戊乙奎醚进行治疗,对照组50例采用阿托品进行治疗,比较两组疗效。结果经治疗,观察组中枢症状消失时间、治愈时间以及住院时间均明显优于对照组,不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论盐酸戊乙奎醚治疗急性有机磷农药中毒疗效较佳,安全可靠,值得临床推广应用。
Objective To investigate the clinical effect of penehyclidine hydrochloride in the treatment of acute organophosphorus pesticide poisoning. Methods One hundred and six patients with organophosphorus pesticide poisoning in our hospital were divided into two groups. 56 cases in the observation group were treated with penehyclidine hydrochloride, and 50 cases in the control group were treated with atropine. The curative effect was compared between the two groups. Results After treatment, the disappearance time, cure time and hospital stay of the central symptom in the observation group were significantly better than those in the control group, and the incidence of adverse reactions was significantly lower than that in the control group (P <0.05). Conclusion Penehyclidine hydrochloride is effective and safe in the treatment of acute organophosphorus pesticide poisoning and is worthy of clinical application.