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众所周知,育龄妇女口服短效甾体激素避孕药物,目前仍是一种最有效的避孕方法。但由于这类药物的一些副作用,因而限制了临床的普遍应用。为解决这个问题,近年来对局部避孕方法又逐渐引起了重视。阴道杀精子避孕药物就是其中研究的一个方面。所谓阴道杀精子避孕药物,就是将一种或数种杀精子药物与一种惰性基质一起制成特定的剂型。用时将其直接放入阴道里。前者起杀精子的作用,后者起机械屏障作用,从而达到避孕。临床上应用的阴道杀精子避孕药中的杀精子剂有:有机汞化合物、表面活性剂以及弱酸等几种。其中醋酸苯汞的应用最普遍。可是近年来发现,这种药物的储
As we all know, women of childbearing age oral short-acting steroid hormone contraceptives, is still one of the most effective contraceptive methods. However, due to some of the side effects of these drugs, which limits the general application of the clinic. In order to solve this problem, more attention has been paid to the method of local contraception in recent years. Vaginal spermicide contraception is one aspect of the study. The so-called vaginal spermicide contraceptives, that is, one or several spermicidal drugs with an inert matrix made of a particular dosage form. Use it directly into the vagina. The former plays the role of spermicidal, which acts as a mechanical barrier to achieve contraception. Clinical application of vaginal spermicidal contraceptives in the spermicide agents are: organic mercury compounds, surfactants and weak acid and several other. Among them, the application of phenylmercuric acetate is the most common. However, in recent years found that the storage of this drug