系统性红斑狼疮(SLE)是一种多系统受累的自身免疫性疾病。白细胞介素(IL)的异常常会导致免疫反应的异常,近年来有关IL在SLE发病过程中所起作用的研究日益增多。本文就IL-8、IL-13、IL-15、IL-16、IL-17和IL-18的研究进展做如下综述。1IL-8IL-8主要由单核巨噬细胞产生。有研究发 SLE is a multisystem autoimmune disease. Abnormalities of interleukin (IL) often lead to abnormal immune response. In recent years, there is an increasing number of studies on the role of IL in the pathogenesis of SLE. This review summarizes the progress of IL-8, IL-13, IL-15, IL-16, IL-17 and IL-18. 1 IL-8 IL-8 is produced mainly by mononuclear macrophages. Research and development