紫杉醇是从紫杉树皮中提取的新型抗肿瘤药物，由于对多种肿瘤有很好的疗效，目前已得到越来越广泛的应用。紫杉醇的细胞学效应是将细胞周期阻断于Ｇ２／Ｍ期，还可诱导多种肿瘤细胞凋亡。紫杉醇结合于微管后如何诱导细胞周期阻断和细胞凋亡，目前仍不清楚。去年我们总结了紫杉 Paclitaxel is a new antitumor drug extracted from the bark of the yew tree. Due to its good curative effect on many kinds of tumors, paclitaxel has been used more and more widely. The cytological effect of paclitaxel is to block the cell cycle G2 / M phase, but also induce apoptosis of a variety of tumors. It remains unclear how paclitaxel induces cell cycle arrest and apoptosis after binding to microtubules. Last year we summarized the yew