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目的:比较单用异丙酚、异丙酚合并瑞芬太尼在无痛人工流产术中的麻醉效能及其对呼吸、循环功能的影响和不良反应。方法:80例早孕患者,无麻醉禁忌证,随机分为两组。组单用1%异丙酚血浆靶控,组在输入异丙酚1min前静脉注射瑞芬太尼,观察术前、睫毛反射消失时、扩宫、吸宫和手术结束时的血压、心率、血氧饱和度值,诱导时间、唤醒时间及异丙酚总用量。结果:与术前比较,组睫毛反应时、扩宫时,BP、HP、SpO2显著降低(P<0.01),吸宫时,BP、HP均增高(P<0.05)。组睫毛反射消失时、扩宫时、吸宫时,BP、HP显著降低(P<0.01),诱导时间组明显缩短(P<0.01),唤醒时间、异丙酚总用量组明显增加(P<0.01)。结论:异丙酚复合瑞芬太尼用于无痛人工流产麻醉效果佳,无呼吸抑制,唤醒时间短,为无痛人工流产麻醉的理想选择。
OBJECTIVE: To compare the anesthetic efficacy of propofol with remifentanil in painless artificial abortion and its effects on respiratory and circulatory function and adverse reactions. Methods: 80 cases of early pregnancy patients without contraindications to anesthesia were randomly divided into two groups. Group 1 with 1% propofol plasma target control, intravenous injection of remifentanil intravenous propofol 1 min before the operation, observe the disappearance of eyelashes, laparotomy, suction Palace and the end of surgery, blood pressure, heart rate, Oxygen saturation value, induction time, wake-up time and the total amount of propofol. Results: Compared with the preoperative, when eyelashes were observed, the numbers of BP, HP and SpO2 were significantly decreased (P <0.01) and the numbers of BP and HP were increased at the time of dilation (P <0.05). When eyelashes reflex disappeared, the levels of BP and HP were significantly decreased (P <0.01), and the time of induction was significantly shorter (P <0.01), and the wake time and total propofol group were significantly increased (P < 0.01). Conclusion: Propofol combined with remifentanil has good analgesia induced abortion, no respiratory depression and short awakening time. It is an ideal choice for painless induced abortion.