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高血压发病、发展过程中存在自主神经功能损害,采用心率变异性(HRV)分析心脏自主神经功能的资料,发现正常血压高值、非杓型高血压及高血压合并靶器官损害等均有心脏自主神经功能损害. HRV可以检测到自主神经功能早期的异常变化,对评价心血管疾病进程中自主神经功能紊乱具有重要的临床价值. 临床上发现二甲双胍、血管紧张素酶转换酶抑制剂、β受体阻滞剂等药物干预后可以改善HRV,恢复心脏自主神经功能的损害.“,”According to the autonomic nerve functional lesion existed in the onset and progression of essential hypertension,here is to make a review of data of the heart rate variability (HRV) analysis on cardi-ac autonomic function,and it has been found cardiac autonomic nerve function lesions exist in patients with high normal blood pressure,non dipper hypertension and hypertension complicated by target organ damage. Detection of heart rate variability can find abnormal autonomic nervous function in early phase , and has important clinical value in the evaluation of autonomic nerve dysfunction in the process of cardiovascular dis-ease.It has been found in clinical practice that metformin,ACEI,Beta-blockers,et.can improve the heart rate variability and recover cardiac autonomic nerve function damage .