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目的分析探讨小儿重症手足口病的临床特征,为重症手足口病的防治提供临床依据。方法回顾性分析2009年6月至2010年6月期间在我院接受治疗的32例重症手足口病患儿的临床资料。结果手足口病好发于3岁以下的患儿,占62.5%,多于发病后1～5d内出现病情恶化;主要合并神经系统并发症,临床表现多样,易发生集体感染甚至流行。本组32例患儿合并颅内感染6例,并心肌炎4例。所有患儿均对症采取抗病毒、注射丙种球蛋白等治疗,全部治愈出院,无任何后遗症。结论重症手足口病易引起严重并发症。临床医生应高度重视,及早干预治疗。并加强认识及疫情报告,以控制疫情扩散。
Objective To analyze the clinical features of pediatric severe hand-foot-mouth disease and provide the clinical evidence for the prevention and treatment of severe hand- foot-mouth disease. Methods The clinical data of 32 severe HFMD patients treated in our hospital from June 2009 to June 2010 were retrospectively analyzed. Results Hand-foot-mouth disease occurred in children under 3 years of age, accounting for 62.5%, more than 1 to 5 days after onset of the disease exacerbations; the main complications of the nervous system, clinical manifestations and diverse, prone to collective infection and even epidemic. The group of 32 children with intracranial infection in 6 cases, and myocarditis in 4 cases. All children were symptomatic to take anti-virus, injection of gamma globulin and other treatment, all cured and discharged, without any sequelae. Conclusion Severe hand, foot and mouth disease can cause serious complications. Clinicians should attach great importance to early intervention. And strengthen awareness and epidemic reports to control the spread of the epidemic.