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目的 探讨导致新生儿畸形的各种可能相关因素。方法 回顾性分析 1995年～ 2 0 0 0年 7年间本院新生儿畸形、死亡的病例。结果 统计分析新生儿畸形 134例 ,占同年围产儿分娩人数 0 .6 5 % ,前三位的新生儿畸形为 :唇腭裂 (19.2 6 % )、先天性心脏病 (15 .6 % )、多指 /并指畸形 (9.6 3% )。新生儿畸形中在第二季度出生者比其他季度高 ,畸形儿男婴较女婴多。相关因素方面 :AB血型孕妇较易分娩神经系统、心血管系统畸形儿。职业是农民的孕妇分娩的新生儿神经系统畸形比率较大 ,母亲是职员的新生儿颜面畸形和唇腭裂所占的比率较大。丈夫饮酒和 /或吸烟者 ,新生儿消化系统、心血管系统畸形比率高。结论 新生儿畸形与孕期病毒感染、母亲血型、职业以及父亲饮酒、吸烟有关。应加强孕前及孕期保健 ,积极开展产前诊断工作 ,降低新生儿畸形率。还应对可能的影响新生儿畸形的各因素进行进一步研究 ,明确各发病因素的相关性。
Objective To explore the possible correlates of neonatal deformity. Methods Retrospective analysis of 7 cases of neonatal deformity and death in our hospital from 1995 to 2000. Results A total of 134 cases of neonatal malformations were analyzed statistically, accounting for 0.56% of the total number of perinatal delivery in the same year. The first three newborn malformations were cleft lip and palate (19.26%), congenital heart disease (15.6%), Means / refers to deformity (9.6 3%). Neonatal malformations were higher in the second quarter than in other quarters, with more malformed baby boys than girls. Related factors: AB blood group pregnant women more prone to birth nervous system, cardiovascular malformations children. Occupation is a farmer pregnant women childbirth newborn nervous system malformations a larger ratio, the mother is a staff member neonatal facial deformity and cleft lip and palate accounted for a larger ratio. Husband drinking and / or smoking, neonatal digestive system, cardiovascular system, a high rate of deformity. Conclusion Neonatal malformation and viral infection during pregnancy, mothers blood type, occupation and father drinking, smoking related. Prenatal and prenatal care should be strengthened and prenatal diagnosis should be actively carried out to reduce neonatal deformity. Should also be possible to affect the neonatal deformity of the various factors for further study, a clear correlation between the incidence of various factors.