目的探讨抗氧化通路酶系NOS2基因多态性与抗结核药物所致肝损伤(anti-tuberculous drug induced liver injury,ATDILI)易感性的相关性。方法采用生物信息统计学方法筛选出NOS2基因16个tagSNP(Hardy-Weinberg平衡P>0.001,最小等位基因频率>0.1,r2>0.8),采用SNPscan™多重SNP分型技术对461例ATDILI患者和
Objective:Acute respiratory distress syndrome (ARDS) is an acute and lethal clinical syndrome that is characterized by the injury of alveolar epithelium,which i