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目的:观察美施康定联合中药辨证对癌痛患者止痛效果的影响。方法:120例患者随机分为治疗组(60例)和对照组(60例);两组均用美施康定初始量为10mg,12h一次,以后随病情用量至理想镇痛。两组患者均静点复方苦参注射液,每天20m1,观察周期4周。治疗组同时用中药辩证论治,观察两组止痛效果的变化情况。结果:治疗后治疗组疼痛控制明显优于对照组(P<0.05);改善美施康定所致的恶心、呕吐、便秘、嗜睡的副反应(P<0.05)。结论:美施康定联合中药辨证治疗癌痛有效提高止痛效果,减少美施康定的副反应,对机体整体功能状态有一个很好的调节作用。
Objective: To observe the effect of Meishi Kangding combined with traditional Chinese medicine on pain relief in patients with cancer pain. Methods: One hundred and twenty patients were randomly divided into treatment group (60 cases) and control group (60 cases). Both groups were given 10 mg once a day for 12 hours and the dosage was adjusted to ideal analgesia. Two groups of patients were static compound Sophora injection, 20m1 day, the observation period of 4 weeks. At the same time, the treatment group dialectical treatment with traditional Chinese medicine, analgesic effect of two groups observed changes. Results: After treatment, the pain control in the treatment group was significantly better than that in the control group (P <0.05). The side effects of nausea, vomiting, constipation and drowsiness were improved (P <0.05). Conclusion: The combination of traditional Chinese medicine and Syndrome Differentiation in the treatment of cancer pain effectively improves the analgesic effect, reduces the side effects of Meishi Kangding and has a good regulating effect on the overall functional status of the body.