深在性红斑狼疮(狼疮性脂膜炎)较罕见,国内报告甚少。著者在7年期间发现14例,与文献报告比较,部分病例有较为特殊之临症表现,现报道如下。典型病例报告例1,女,28岁,病期1年,初诊:SLE 颜面及四肢发生水肿性红色斑块及结节红斑。前者持久不退,后者经2-4周可自然消失。有痒感或微痛感。既往有关节痛。检查:面部两侧各有1片5×6cm~2大小、界线不清的肿性斑块,其中心部有约两分币大小的红斑,表面角化并有粘着性脱屑及毛囊口扩大。其下有硬结。两手有红斑、丘疹及结节红斑。两足亦有红斑及萎缩性皮疹。两侧颈部及腋下淋巴结肿大,有触痛。化验:血WBC3500;血沉25mm;尿蛋白(+);ANA1:80(+);LEC(-);免疫球蛋白值正常;C_3值正常;血浆蛋白电泳值正常, Deep in lupus erythematosus (lupus panniculitis) is rare, few domestic reports. Author in the 7-year period found in 14 cases, compared with the literature report, some cases have a more specific clinical manifestations are reported below. Case Report 1, female, 28 years old, 1-year disease, newly diagnosed: SLE facial and limb edema occurred erythema and erythema nodosum. The former durable, the latter after 2-4 weeks can disappear naturally. Itching or slight pain. Past joint pain. Check: Each side of the face has a 5 × 6cm ~ 2 size, boundary clear plaque, the center of about two minutes in the size of the erythema, keratosis and facial adhesions and hair follicles to expand the mouth . There are induration under it. Both hands have erythema, papules and erythema nodosum. Two feet also have erythema and atrophic rash. Both sides of the neck and armpit lymph nodes, tenderness. Assay: blood WBC3500; erythrocyte sedimentation rate 25mm; urinary protein (ANA1: 80 (+); LEC (-); normal immunoglobulin value; normal C_3 value; normal plasma protein electrophoresis,