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目的评价尿激酶静脉溶栓治疗超早期脑梗死的效果。方法治疗组50例:尿激酶100万~150万单位+生理盐水100ml,40～50min内滴完。同时给予奥扎格雷钠80mg及胞二磷胆碱1.0日一次静点。溶栓前根据指征严格筛选病例,溶栓过程中加强监护,溶栓后观察记录疗效、不良反应。同时选择50例对照组行常规治疗:给予奥扎格雷钠80mg及胞二磷胆碱1.0日1次静点。结果治疗组疗效显著高于对照组(P<0.05)。比较两组CSS及日常活动量评分。结论尿激酶静脉溶栓治疗超急性期脑梗死效果显著,致残率低。在严格监护安全性较高。
Objective To evaluate the effect of intravenous thrombolysis with urokinase in the treatment of ultra-early cerebral infarction. Methods 50 cases of treatment group: urokinase 1 million to 150 million units + saline 100ml, 40 ~ 50min drip finished. At the same time given ozagrel sodium 80mg and citicoline 1.0 point of a static. According to the indications before thrombolysis, the patients were screened strictly, the monitoring was strengthened during thrombolysis, and the curative effect and adverse reactions were observed and recorded after thrombolysis. At the same time choose 50 cases of control group routine treatment: given sodium ozagrel 80mg and citicoline 1.0 point 1 time. Results The treatment group was significantly higher than the control group (P <0.05). The CSS and daily activity scores of two groups were compared. Conclusions Urokinase intravenous thrombolysis is effective in treating hyperacute cerebral infarction with low morbidity. High security in strict supervision.