慢性肾脏疾病患者激素的排泄和降解均有显著失调,其中甲状腺、甲状旁腺及下丘脑-垂体-性腺轴的异常已得到充分证实。这些异常使一些有关内分泌功能的实验室检查结果难以解释,儿茶酚胺类及其代谢产物的检查尤其如此。慢性肾衰功能衰竭(肾衰)患者无论有否高血压,其血浆儿茶酚胺类物质均升高,这种升高可见于仅有轻度肾功能不全者,亦见于需作维持性血液透析的终末期尿毒症患者。轻至中度慢性肾衰患者血浆去甲 Hormone excretion and degradation in patients with chronic kidney disease have significant disorders, including thyroid, parathyroid and hypothalamus - pituitary - gonad axis abnormalities have been fully confirmed. These abnormalities make some laboratory tests of endocrine function difficult to interpret, especially catecholamines and their metabolites. Patients with chronic renal failure (renal failure) regardless of whether the high blood pressure, plasma catecholamines are elevated, this increase can be seen in only mild renal insufficiency, also see the need for maintenance hemodialysis End-stage uremic patients. Patients with mild to moderate chronic renal failure to the plasma