论文部分内容阅读
目的探讨乳腺癌手术前哨淋巴结(SLN)活检的临床应用价值。方法 65例外科手术治疗乳腺癌患者,在乳晕周围或病灶周围取4个点行皮下注射亚甲蓝,定位前哨淋巴结,然后行前哨淋巴结活检,术后全部淋巴结送病理检查。结果 65例患者中,共61例成功检测出前哨淋巴结,病理证实:前哨淋巴结45例阳性,16例阴性者,腋窝淋巴结47例阳性,假阴性2例,检出率93.8%;准确率96.7%;敏感度95.7%,假阴性率4.3%。结论乳腺癌前哨淋巴结活检可以准确反映早期乳腺癌患者腋窝淋巴结转移状态,为患者手术方式、分期、放化疗方案的制定、预后的判断提供证据。
Objective To investigate the clinical value of sentinel lymph node (SLN) biopsy in breast cancer surgery. Methods Sixty - five patients with breast cancer were treated surgically. Methylene blue was subcutaneously injected at 4 points around the areola or around the lesion. The sentinel lymph node was located. The sentinel lymph node biopsy was performed. All the lymph nodes were pathologically examined. Results Of the 65 patients, 61 cases were successfully detected with sentinel lymph nodes. The pathology confirmed that 45 sentinel lymph nodes were positive, 16 were negative, 47 were axillary lymph nodes, 2 were false negatives, the detection rate was 93.8% and the accuracy was 96.7% The sensitivity was 95.7% and the false negative rate was 4.3%. Conclusions Sentinel lymph node biopsy of breast cancer can accurately reflect the status of axillary lymph node metastasis in patients with early stage breast cancer and provide evidence for the operation mode, staging, radiotherapy and chemotherapy regimen, and prognosis judgment.