目的探讨原发性胃肠道淋巴瘤多层螺旋计算机断层扫描(CT)表现及临床价值。方法选取2013年4月至2014年12月间收治的60例原发性胃肠道淋巴瘤患者。其中胃部原发性淋巴瘤患者35例,肠道淋巴瘤患者25例;黏膜相关淋巴组织(MALT)淋巴瘤患者20例,其他病理类型40例。比较胃部原发性淋巴瘤、肠道淋巴瘤、MALT和其他类型淋巴瘤的病变厚度、平扫CT值和增强CT值。结果胃部原发性淋巴瘤病变厚度、平均CT值和增强CT值分别为(0.45±1.89)cm、(52.0±3.7)HU和(88.3±8.9)HU,肠道原发性淋巴瘤分别为(1.72±0.96)cm、(38.6±6.2)HU和(62.9±11.1)HU,差异均有统计学意义(均P<0.05)。MALT淋巴瘤病变厚度、平均CT值和增强CT值分别为(0.68±0.34)cm、(32.0±3.4)HU和(98.3±8.2)HU,其他病理类型分别为(1.45±0.56)cm、(51.3±6.3)HU和(76.2±7.4)HU,差异均有统计学意义(均P<0.05)。结论原发性胃肠道淋巴瘤在不同发病部位和不同病理类型间多层螺旋CT表现有显著差异,多层螺旋CT在原发性胃肠道淋巴瘤检测方面效果明显,值得临床应用推广。 Objective To investigate the clinical manifestations and clinical value of multi-slice helical computed tomography (CT) of primary gastrointestinal lymphoma. Methods Sixty patients with primary gastrointestinal lymphoma who were admitted between April 2013 and December 2014 were selected. Among them, 35 were patients with primary gastric lymphoma, 25 were patients with intestinal lymphoma, 20 were patients with mucosal-associated lymphoid tissue (MALT) lymphoma and 40 were other pathological types. The lesions were compared between gastric primary lymphoma, intestinal lymphoma, MALT and other types of lymphoma, CT scan and CT scan. Results The pathological changes, mean CT values ​​and enhanced CT values ​​of gastric primary lymphoma were (0.45 ± 1.89) cm, (52.0 ± 3.7) HU and (88.3 ± 8.9) HU, respectively. The primary intestinal lymphoma were (1.72 ± 0.96) cm, (38.6 ± 6.2) HU and (62.9 ± 11.1) HU, respectively. The differences were statistically significant (all P <0.05). MALT lymphoma lesion thickness, average CT value and enhanced CT value were (0.68 ± 0.34) cm, (32.0 ± 3.4) HU and (98.3 ± 8.2) HU, respectively, and the other pathological types were (1.45 ± 0.56) cm and ± 6.3) HU and (76.2 ± 7.4) HU, respectively (all P <0.05). Conclusions Multi-slice spiral CT has obvious difference in different sites and pathological types of primary gastrointestinal lymphoma. Multi-slice spiral CT has obvious effect in the detection of primary gastrointestinal lymphoma, which is worthy of clinical application.