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目的了解老年甲状腺相关眼病患者视觉相关生存质量现状,并探讨其影响因素,为改善患者生存质量提供理论依据。方法选择2014年2—12月到武汉大学人民医院眼科就诊的老年甲状腺相关眼病患者139例作为甲状腺相关眼病组,同时选取139例健康老年人作为对照组。采用中文版视功能相关生存质量-25,对两组研究对象进行生存质量评估,并选取性别、受教育程度、不同病情分组、复视、甲状腺功能低下(甲低)史、家庭氛围、医疗费用支付方式几个可能导致患者生存质量下降的因素进行统计学分析。结果老年甲状腺相关眼病患者视觉功能相关生存质量总均分为35.69±14.05,健康老年人生存质量总均分为50.78±16.10,差异有统计学意义(P≤0.05);单因素分析显示,不同病情分组、复视、甲低史、家庭氛围、医疗费用支付方式均是老年甲状腺相关眼病患者生存质量的影响因素,P≤0.05;logistic回归分析显示病情严重程度、复视、甲低史、家庭氛围均是生存质量的显著影响因素,P≤0.05。结论老年甲状腺相关眼病患者视觉功能相关生存质量较健康老年人下降,病情严重程度、复视、甲低史是生存质量的危险因素,家庭氛围是生存质量的保护因素。
Objective To understand the status quo of visual related quality of life in elderly patients with thyroid associated ophthalmopathy and to explore its influencing factors so as to provide theoretical basis for improving patients’ quality of life. Methods A total of 139 patients with senile thyroid associated ophthalmopathy who received ophthalmology from Wuhan University People’s Hospital from January to December 2014 were selected as the thyroid-associated ophthalmopathy group and 139 healthy controls were selected as the control group. The quality of life of the two groups of subjects was assessed by using the Chinese version of Quality of Life -25, and the gender, education level, different disease groups, diplopia, hypothyroidism, hypothyroidism, family environment, medical expenses Methods of payment Several factors that may lead to a decline in the quality of life of patients were statistically analyzed. Results The overall mean quality of life related to visual function in elderly patients with thyroid associated ophthalmopathy was 35.69 ± 14.05. The overall mean quality of life of healthy elderly was 50.78 ± 16.10, with significant difference (P≤0.05). Univariate analysis showed that different conditions Grouping, diplopia, hypothyroidism, family atmosphere, payment of medical costs are the influencing factors of the quality of life in elderly patients with thyroid associated ophthalmopathy, P≤0.05; logistic regression analysis shows the severity of the illness, diplopia, hypothyroidism, family atmosphere All of them were significant influencing factors of quality of life, P≤0.05. Conclusion The quality of life related to visual function in elderly patients with thyroid associated ophthalmopathy is lower than that in healthy elderly. The severity of illness, diplopia and hypothyroidism are risk factors of quality of life. Family environment is the protective factor of quality of life.