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目的观察静脉滴注尼卡地平治疗重症高血压的临床疗效及不良反应。方法40例重症高血压患者采用尼卡地平注射液10mg加入5%葡萄糖注射液或0.9%氯化钠注射液250ml持续静滴,速度0.4～0.8μg/kg.min。结果尼卡地平给药后8分钟,血压开始下降,30分钟时血压下降20%,无明显副作用。结论尼卡地平能迅速降低血压,无明显副作用,用药安全,疗效显著,应用范围广,适用于多数重症高血压患者。
Objective To observe the clinical efficacy and adverse reactions of intravenous nicardipine in the treatment of severe hypertension. Methods Forty patients with severe hypertension were treated with nicardipine injection 10mg and 5% dextrose injection or 0.9% sodium chloride injection 250ml for continuous intravenous infusion at the speed of 0.4-0.8μg / kg.min. Results Nicardipine 8 minutes after administration, blood pressure began to decline, 30 minutes when the blood pressure decreased by 20%, no significant side effects. Conclusions Nicardipine can reduce blood pressure rapidly without obvious side effects, and it is safe in use and has obvious curative effect and wide application range. It is suitable for most severe hypertensive patients.