角膜是位于眼球前部的透明组织,起着眼球保护膜和“透光窗”的重要功能。角膜上皮的更新及创伤愈合过程,有赖于角膜缘干细胞的增殖、移行。当角膜缘干细胞缺失,会使角膜上皮增殖能力丧失、屏障功能下降,致使眼部出现不同程度的病理改变。角膜缘干细胞(Limbal stem cells,LSCs) The cornea is a transparent tissue located in the anterior part of the eyeball that plays an important role in the protective membrane and “light-transmissive window” of the eye. Corneal epithelial regeneration and wound healing process, depends on the limbal stem cell proliferation, migration. When the corneal limbal stem cells are missing, the proliferation of corneal epithelial cells will be lost, barrier function decreased, resulting in varying degrees of ocular pathological changes. Limbal stem cells (LSCs)