目的探讨集束化护理在经鼻呼吸道正压通气辅助治疗婴幼儿重症肺炎合并呼吸衰竭中的应用效果。方法选取2014年6月至2016年7月濮阳市人民医院收治的经鼻呼吸道正压通气辅助治疗的重症肺炎合并呼吸衰竭婴幼儿120例,根据入院时间分为两组,各60例。对照组实施常规护理,观察组应用集束化护理。对比两组护理效果及机械通气时间、住院时间。结果护理后,观察组护理总有效率为93.33%,高于对照组总有效率80.00%,差异有统计学意义(P<0.05);观察组机械通气时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。结论集束化护理可提高婴幼儿重症肺炎合并呼吸衰竭经鼻呼吸道正压通气辅助治疗总有效率,缩短机械通气时间及住院时间。 Objective To explore the application of cluster nursing in the treatment of severe pneumonia complicated with respiratory failure in children with nasal positive airway pressure. Methods From June 2014 to July 2016, 120 infants with severe pneumonia complicated by respiratory failure were enrolled in Puyang Municipal People’s Hospital who were treated with positive airway pressure ventilation. They were divided into two groups according to admission time, 60 cases each. The control group underwent routine care and the observation group received intensive care. Compare the two groups of nursing effects and mechanical ventilation time, hospital stay. Results After the nursing, the total effective rate of the observation group was 93.33%, higher than that of the control group, the total effective rate was 80.00%, the difference was statistically significant (P <0.05); the observation group’s mechanical ventilation time and hospitalization time were shorter than the control group, There was statistical significance (P <0.05). Conclusions The cluster nursing can improve the total effective rate of nasal respiratory system positive airway pressure assisted treatment of severe pneumonia and respiratory failure in infants and young children, and shorten the duration of mechanical ventilation and hospital stay.