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阻塞性睡眠呼吸暂停低通气综合征（OSAHS）发病率逐年升高，已经成为危害人类健康的主要疾病之一。迄今为止，OSAHS 的发病机制尚未阐明。成纤维细胞生长因子21（FGF21）是参与糖脂代谢的一种重要蛋白质。近年来大量的研究显示 FGF21与 OSAHS 的发生发展有密切的联系。本文就近些年 OSAHS 与 FGF21的相关研究进行简要综述。“,”The prevalence of OSAHS has been dramatically increasing during the last decade,which has become one of the major diseases that endangers human health.The pathogenesis of OSAHS is not yet fully clear.Some studies have shown that FGF21 is closely linked with OSAHS.The correlation between FGF21 and OSAHS will be discussed in this chapter.