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脑CT 增强检查需要静脉内注入大量造影剂。应用常规造影剂多数病人会出现发热感和金属味,其它不常见反应有恶心,呕吐、荨麻疹和血压下降。Iohexol 是一种新的非离子型造影剂,具有与阿米培克相同的优点,它是一种便于使用的溶液制剂,比阿米培克更实用。作者用随机化双盲法比较Iohexol 和Metriz-oate 在增强检查中的副作用和强化效果。结果Me-trizoate 组105例有10例出现副作用(包括恶心、呕吐、喷嚏、皮肤搔痒和荨麻疹),而Iohexol 组105例仅一例出现恶心,其差异具有统计学意义。
Brain CT enhancement requires intravenous injection of a large amount of contrast agent. Most patients with conventional contrast agents experience fever and metallic taste. Other uncommon reactions are nausea, vomiting, urticaria, and blood pressure. Iohexol is a new non-ionic contrast agent with the same advantages as Amipex®. It is a convenient solution formulation that is more practical than Amiconek. The authors compared the side effects and enhancement effects of Iohexol and Metriz-oate in enhanced examinations using a randomized, double-blind method. RESULTS: There were 105 side effects (including nausea, vomiting, sneezing, pruritus, and urticaria) in 105 patients in the Me-trizoate group, and only 105 patients in the Iohexol group had nausea. The difference was statistically significant.