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T细胞受体(TCR)识别抗原与抗体识别抗原是不同的。前者识别的是抗原—主要组织相容性抗原的复合物,受MHC限制,而后者则是识别天然状态下的抗原,亲和力较强。考虑到TCR变区部位与抗体变区部位有众多相似之处,即其均由两条二硫键相连的多肽组成,TCR由a、p链组成,抗体则由
The T cell receptor (TCR) recognition antigen is different from the antibody recognition antigen. The former identifies antigen-major histocompatibility antigen complexes that are restricted by MHC, while the latter recognizes antigens in the natural state with strong affinity. Considering that there are many similarities between the TCR variant region and the antibody variant region, that is, they all consist of two disulfide-linked polypeptides, TCR consists of a and p chains, and antibodies