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藁本内酯(Ligustilide)是当归(Angelica sinensis Diels)和欧当归(Livisticum officinale koch)根挥发油中的主要成分。已报道当归和欧当归挥发油中含藁本内酯分别约为60%和35%。三桥博等人报道藁本内酯是一种新的活性物质。两种挥发油有相似的药理活性,对大鼠离体子宫有抑制其节律性收缩的作用。
Ligustilide is the main component of the essential oil of Angelica sinensis Diels and Livisticum officinale koch. It has been reported that ligustic lactones in angelica and angelica volatile oils are approximately 60% and 35%, respectively. Sanqiao Bo et al. reported that ligustilide is a new active substance. Both volatile oils have similar pharmacological activity and have the effect of inhibiting rhythmic contraction of isolated rat uterus.