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目的:探讨如何提高卵巢外腹膜浆液性乳头状癌(EPSPC)的临床诊断率及疗效。方法:对3例EPSPC的临床资料进行回顾性分析。结果:3例患者经过临床、B超及肿瘤标记物的检查后,均在术前做出了诊断。在一个疗程的先期化疗后,3例患者接受了肿瘤细胞减灭术及含铂类药物的联合化疗2～9个疗程。除1例失访外,其余2例病情得到完全控制,至今无复发迹象。1例已存活78个月,另一例20个月。结论:通过早期诊断,实施彻底的肿瘤细胞减灭术,术后及时给予足量含铂类药物的联合化疗,可显著改善EPSPC患者的预后。
Objective: To explore how to improve the clinical diagnosis rate and curative effect of extraperitoneal ovarian peritoneal serous papillary carcinoma (EPSPC). Methods: Three cases of EPSPC clinical data were retrospectively analyzed. Results: Three patients were diagnosed preoperatively after clinical examination, B ultrasound and tumor marker. After a course of chemotherapy, three patients underwent cytoreductive surgery and 2 to 9 courses of combined chemotherapy with platinum. In addition to a lost case, the remaining two cases were fully controlled and no recurrence so far. One patient survived 78 months and the other 20 months. Conclusion: Through early diagnosis and thorough tumor cytoreduction, timely and sufficient platinum-containing drugs combined with chemotherapy can significantly improve the prognosis of patients with EPSPC.