本文比较了5例胰岛细胞抗体阳性(ICA_s~+)和5例配对的胰岛细胞抗体阴性(ICA_s~-)的非胰岛素依赖型糖尿病(NIDDM)患者以及7例正常对照的口服葡萄糖耐量实验(OGTT)结果。NIDDM 组血糖显著高于正常对照组,胰岛素/血糖则低于对照组。ICA_s~+组的胰岛素、胰岛素/血糖显著低于 ICA_s~-组。经果提示:ICA_s~+的 NIDDM 患者的胰岛β细胞功能低于配对的ICA_s~-者。 In this study, 5 patients with positive islet cell antibodies (ICA s ~ +) and 5 matched non-insulin dependent diabetes mellitus (NIDDM) patients with islet cell antibody negative (ICA s ~ -) were compared with 7 normal controls for oral glucose tolerance test (OGTT )result. Blood glucose in NIDDM group was significantly higher than that in normal control group, and insulin / blood glucose was lower than that in control group. ICA_s ~ + group insulin, insulin / blood glucose was significantly lower than the ICA_s ~ - group. The results suggest that: ICA_s ~ + NIDDM patients with pancreatic β-cell function is lower than the matched ICA_s ~ -.