在抗肿瘤免疫中,肿瘤特异性T细胞应答,特别是CD8+T细胞(cytotoxic T cell,CTL)对肿瘤细胞的杀伤是至关重要的免疫保护机制,肿瘤特异性CD4+T细胞分泌的IFN-γ(interferon-γ,IFN-γ)以及肿瘤抗原特异性IgG(immunoglobulin G,IgG)抗体也具有重要的清除肿瘤的功能。常见的恶性肿瘤如宫颈癌、鼻咽癌等恶性肿瘤均存在免疫 Tumor-specific T cell responses, particularly cytotoxic T cell (CTL) killing of tumor cells, are crucial immune protective mechanisms in antitumor immunity. Tumor-specific CD4 + T cell-secreting IFN The interferon-γ (IFN-γ) and tumor immunoglobulin G (IgG) antibodies also have important tumor clearance functions. Common malignant tumors such as cervical cancer, nasopharyngeal carcinoma and other malignancies are immune