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七十年代以来,随着免疫学及成份输血、抗感染等辅助疗法的进展,同种骨髓移植做为难治性白血病、再生不良性贫血的一种疗法又被应用于临床,并取得了良好的成绩.1976年Thomas报告了100例难治性白血病的同种骨髓移植,其中18例尚存活,最长者达五年之久. 目前,由于联合化疗及辅助疗法的发展,急性白血病的完全缓解率和存活期得到了提高和延长.对于难治性白血病如果给予超出一般的大量的强有力的治疗,可以使白血病细胞灭绝.可是,这样的治疗会给
Since the seventies, with the progress of immunological and component blood transfusions, anti-infection and other adjuvant therapy, allogeneic bone marrow transplantation as a refractory leukemia, a treatment of aplastic anemia has been applied to clinical and achieved good Results Thomas reported 100 allogeneic bone marrow transplants of refractory leukemia in 1976, 18 of whom survived for a maximum of 5 years.At present, due to the development of combination chemotherapy and adjuvant therapy, complete remission of acute leukemia Rate and survival have been increased and extended for the treatment of refractory leukemia if given more than the usual large number of powerful treatment can extinction of leukemia cells.However, such treatment will give