目的：探讨术中荧光造影在颅内前循环动脉瘤显微手术治疗中的应用价值。方法前瞻性观察45例手术治疗的颅内前循环动脉瘤患者，术前采用CT脑动脉三维重建确诊；术中应用Pentero手术显微镜进行吲哚菁绿荧光造影（indocyanine green angiography，ICGA），术后常规数字减影脑血管造影（digital subtraction angiography，DSA），对比观察术中影像与术后影像检查结果符合情况；随访6～12月应用改良Rankin评分（modified Rankin Scale，mRS）评价预后。结果术中ICGA可清楚显示动脉瘤与载瘤血管及周围穿支动脉的关系，其观察结果与术后DSA显示的动脉瘤颈残余、载瘤动脉狭窄、穿支动脉闭塞的情况基本符合；本组无死亡，手术相关并发症4.4%，治疗优良率91.1%（mRS<3）。结论术中ICGA为颅内前循环动脉瘤的显微手术提供丰富的血管结构和血流信息，有助于动脉瘤的安全夹闭以及穿支血管完整保留。“,”Objective Indocyanine green angiography (ICGA) is a promising technique for assessment of clipping for intracranial aneurysms. The present study was to examine Intra-operative ICGA may help for clipping of anterior cir-culation aneurysms. Methods Forty-five patients with anterior circulation aneurysms undergoing clipping were included. Pre-operative CTA was obtained to analyze the location, direction, size and shape of the aneurysms. Intra-operative ICGA was performed on Pentero microscope. Routine digital subtraction angiography (DSA) were obtained. Coincidence of ICGA and DSA was analyzed. Clinical outcome was evaluated using modified Rankin scale in 6 to 12 months after surgery. Re-sults Aneurysm’s parent artery and perforating branches were illustrated clearly on ICGA. Coincidence of ICGA and DSA for aneurysm remnant, patent artery narrowing and perforating branch occlusion were 97.8%, 93.3%and 91.1%, respec-tively. Conclusion Intra-operative ICGA is a quick, reliable and cost-effective assessment method of anterior circula-tion clipping, which may be useful during routine aneurysm surgery as an independent assessment or as an adjunct to intra-operative or postoperative DSA.