清金化痰汤联合左氧氟沙星治疗痰热郁肺型社区获得性肺炎随机平行对照研究

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[目的]观察清金化痰汤联合左氧氟沙星治疗痰热郁肺型社区获得性肺炎疗效。[方法]使用随机平行对照方法,将42例门诊患者按随机数字表法分为两组,对照组21例左氧氟沙星0.4+0.9%生理盐水或5%葡萄糖250mL,1次/d,静滴。治疗组21例清金化痰汤(黄芩、山栀子各12g,桔梗、麦冬各9g,桑白皮15g,贝母9g,知母、栝楼仁各15g,橘红、茯苓各9g,甘草3g)1剂/d,水煎200mL,早晚口服,左氧氟沙星治疗同对照组。连续治疗10d为1疗程。观测临床症状、体温、咳嗽及肺啰音、胸部影像、不良反应。治疗1疗程,判定疗效。[结果]治疗组治愈13例,显效6例,有效2例,无效0例,总有效率100%。对照组治愈5例,显效8例,有效5例,无效3例,总有效率85.71%。治疗组疗效优于对照组(P<0.05)。[结论]清金化痰汤联合左氧氟沙星治疗痰热郁肺型社区获得性肺炎,疗效满意,无副作用,值得推广。 [Objective] To observe the curative effect of Qingjin Huatan Decoction combined with levofloxacin on sputum, heat and lung-type of community-acquired pneumonia. [Methods] 42 cases of outpatients were randomly divided into two groups according to a randomized parallel table. The control group consisted of 21 levofloxacin 0.4 + 0.9% saline or 250% 5% glucose, once a day. 21 cases of Qingjin Huatan Decoction (Scutellaria baicalensis, Gardenia jasminoides 12g, Campanulaceae, Ophiopogon japonicus 9g, Morus alba 15g, Fritillaria 9g, Anemarrhena, Tailou Ren each 15g, orange red, Poria 9g, licorice 3g) 1 dose / d, decoction 200mL, sooner or later oral levofloxacin treatment with the control group. Continuous treatment of 10d for a course of treatment. Observation of clinical symptoms, body temperature, cough and pulmonary rales, chest images, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] In the treatment group, 13 cases were cured, 6 cases markedly effective, 2 cases effective, 0 ineffective and the total effective rate was 100%. In control group, 5 cases were cured, 8 cases were markedly effective, 5 cases were effective and 3 cases were ineffective. The total effective rate was 85.71%. The treatment group was better than the control group (P <0.05). [Conclusion] Qingjin Huatan Decoction combined with levofloxacin in the treatment of phlegm-heat type of lung-acquired community-acquired pneumonia has satisfactory curative effect and no side effects and is worthy of popularization.
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