In this paper, progress in strain study of blocks and faults by GPS data are discussed, and the concept that active structures between blocks are the main body of crustal strain is clarified. By energy transfer principle of elastic mechanics, the relation between strain around faults and tectonic force on fault surfaces is set up and main body element model of crustal strain is constructed. Finally, the relation between mechanical evolution of model and seismogenic process of Kunlun earthquake (MS=8.1) is discussed by continuous GPS data of datum stations. The result suggests that the relatively relaxed change under background of strong compressing and shearing may help to trigger moderate-strong earthquakes. In this paper, progress in strain study of blocks and faults by GPS data are discussed, and the concept that active structures between blocks are the main body of crustal strain is clarified. By energy transfer principle of elastic mechanics, the relation between strain around faults and tectonic force on fault surfaces is set up and main body element model of crustal strain is constructed. Finally, the relation between mechanical evolution of model and seismogenic process of Kunlun earthquake (MS = 8.1) is discussed by by continuous GPS data of datum stations. The result suggests that the relatively relaxed change under background of strong compressing and shearing may help to trigger moderate-strong earthquakes.