A uniform wire segmentation algorithm for performance optimization of distributed RLC interconnects was proposed in this paper. The optimal wire length for identical segments and buffer size for buffer insertion are obtained through computation and derivation, based on a 2-pole approximation model of distributed RLC interconnect. For typical inductance value and long wires under 180nm technology, experiments show that the uniform wire segmentation technique proposed in the paper can reduce delay by about 27% ～ 56% , while requires 34%～69% less total buffer usage and thus 29% to 58% less power consumption. It is suitable for long RLC interconnect performance optimization.