单克隆抗体(McAb)及淋巴细胞杂交瘤技术是当前免疫学中最重要的新技术之一。近年来发表的免疫学文献中约40—50%与它有关。它被广泛用于免疫学、医学及生物学的许多领域的研究,推动着这些学科向分子水平发展。国内有关这方面的研究工作正在起步。本文仅对单克隆抗体及杂交瘤技术作一简略介绍。一、单克隆抗体的基本概念及主要特点克降(clone)就是细菌或细胞分裂形成的集 Monoclonal antibody (McAb) and lymphocyte hybridoma technology is one of the most important new technologies in immunology. About 40-50% of immunology articles published in recent years have been associated with it. It is widely used in many fields of immunology, medicine and biology to promote the development of these disciplines to the molecular level. Domestic research work in this area is starting. This article only on the monoclonal antibody and hybridoma technology for a brief introduction. First, the basic concepts of monoclonal antibodies and the main characteristics Clone (clone) is the bacterial or cell division formed