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目的探讨脉络宁注射液醇沉废弃物(简称MFP)对雏鸡免疫系统和生长性能的影响。方法将1日龄雏鸡随机分为4组,即空白组予以正常饮水,实验组饮水中分别给予醇沉物浓度为1%、3%、5%,每组20羽雏鸡,连续饲养42 d。雏鸡7日龄和21日龄进行新城疫活疫苗免疫;分别于3、10、17、24、31、38日龄测定各组雏鸡的平均体质量(每周/次)、料肉比,观察雏鸡的生长性能;21日龄和42日龄雏鸡的血清总蛋白、血清球蛋白、新城疫抗体水平和免疫器官指数,并观察21日龄及42日龄各组雏鸡的胸腺、脾和法氏囊组织结构。结果实验各组与空白组比较,体质量离散程度明显减小,集中趋势增强;血清总蛋白、球蛋白和新城疫抗体水平均增高,且21日龄雏鸡实验组的球蛋白及新城疫抗体水平显著高于空白组(P<0.05);免疫器官淋巴细胞排列更紧密,数量增多。结论脉络宁注射液醇沉废弃物可用于雏鸡的饲养,每日在饮水中添加1%~5%的醇沉物可显著提高雏鸡的免疫力,减少其生长过程的个体差异。此外,本研究为中药废弃物的资源化利用提供了一条可供参考的途径。
Objective To investigate the effects of Mailuoning injection alcohol precipitation (MFP) on the immune system and growth performance of chickens. Methods One-day-old chickens were randomly divided into four groups, namely the blank group was given normal drinking water, and the experimental group was given alcohol sediment concentration of 1%, 3%, 5%, 20 chicks in each group. The chickens were immunized with the Newcastle disease live vaccine on the 7th and 21st days of age. The average body weight (weekly / times), feed conversion ratio and the ratio of meat to meat of each group were measured at 3, 10, 17, 24, 31 and 38 days The growth performance of chickens, serum total protein, serum globulin, Newcastle disease antibody levels and immune organ index of 21-day-old and 42-day-old chickens were observed. Thymus, spleen and Fahrenheit Pouch tissue structure. Results Compared with the blank group, the dispersion of body weight in each group was significantly reduced and the concentration tendency was enhanced. The levels of serum total protein, globulin and Newcastle disease antibody were increased in each group, and the globulin and Newcastle disease antibody levels in the 21-day-old chick Significantly higher than that in the blank group (P <0.05). The lymphocytes of immune organs were arranged more closely and the number increased. Conclusion Mailuoning injection alcohol precipitation can be used for raising chickens. Daily addition of 1% ~ 5% alcohol precipitates to chickens can significantly improve the immunity of chickens and reduce their individual differences in growth. In addition, this study provides a reference for the resource-based utilization of traditional Chinese medicine waste.